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Matrix Rigidity Induces Osteolytic Gene Expression of Metastatic Breast Cancer Cells
Nearly 70% of breast cancer patients with advanced disease will develop bone metastases. Once established in bone, tumor cells produce factors that cause changes in normal bone remodeling, such as parathyroid hormone-related protein (PTHrP). While enhanced expression of PTHrP is known to stimulate o...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981576/ https://www.ncbi.nlm.nih.gov/pubmed/21085597 http://dx.doi.org/10.1371/journal.pone.0015451 |