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On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039

RATIONALE: Several studies have suggested that modulation of the glutamatergic system could be a new, efficient way to achieve antidepressant activity. Behavioral data showed that group II mGlu receptor antagonists (i.e., (1R, 2R, 3R, 5R, 6R)-2-amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo[3.1.0]h...

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Detalles Bibliográficos
Autores principales: Pałucha-Poniewiera, Agnieszka, Wierońska, Joanna M., Brański, Piotr, Stachowicz, Katarzyna, Chaki, Shigeyuki, Pilc, Andrzej
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981731/
https://www.ncbi.nlm.nih.gov/pubmed/20703449
http://dx.doi.org/10.1007/s00213-010-1978-5