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Tracing antigen signatures in the human IgE repertoire

Allergen recognition by IgE antibodies is a key event in allergic inflammation. In this study, the IgE IGHV repertoires of individuals with allergy to the major birch pollen allergen, Bet v 1, were analyzed over a four years period of allergen exposure by RT-PCR and sequencing of cDNA. Approximately...

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Detalles Bibliográficos
Autores principales: Marth, Katharina, Novatchkova, Maria, Focke-Tejkl, Margarete, Jenisch, Stefan, Jäger, Siegfried, Kabelitz, Dieter, Valenta, Rudolf
Formato: Texto
Lenguaje:English
Publicado: Pergamon Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981859/
https://www.ncbi.nlm.nih.gov/pubmed/20573403
http://dx.doi.org/10.1016/j.molimm.2010.05.285