Applying bioinformatics for antibody epitope prediction using affinity-selected mimotopes – relevance for vaccine design

To properly characterize protective polyclonal antibody responses, it is necessary to examine epitope specificity. Most antibody epitopes are conformational in nature and, thus, cannot be identified using synthetic linear peptides. Cyclic peptides can function as mimetics of conformational epitopes...

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Detalles Bibliográficos
Autores principales: Denisova, Galina F, Denisov, Dimitri A, Bramson, Jonathan L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981875/
https://www.ncbi.nlm.nih.gov/pubmed/21067548
http://dx.doi.org/10.1186/1745-7580-6-S2-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981875/
https://www.ncbi.nlm.nih.gov/pubmed/21067548
http://dx.doi.org/10.1186/1745-7580-6-S2-S6

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