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Applying bioinformatics for antibody epitope prediction using affinity-selected mimotopes – relevance for vaccine design
To properly characterize protective polyclonal antibody responses, it is necessary to examine epitope specificity. Most antibody epitopes are conformational in nature and, thus, cannot be identified using synthetic linear peptides. Cyclic peptides can function as mimetics of conformational epitopes...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981875/ https://www.ncbi.nlm.nih.gov/pubmed/21067548 http://dx.doi.org/10.1186/1745-7580-6-S2-S6 |