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State of the art and challenges in sequence based T-cell epitope prediction

Sequence based T-cell epitope predictions have improved immensely in the last decade. From predictions of peptide binding to major histocompatibility complex molecules with moderate accuracy, limited allele coverage, and no good estimates of the other events in the antigen-processing pathway, the fi...

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Detalles Bibliográficos
Autores principales: Lundegaard, Claus, Hoof, Ilka, Lund, Ole, Nielsen, Morten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981877/
https://www.ncbi.nlm.nih.gov/pubmed/21067545
http://dx.doi.org/10.1186/1745-7580-6-S2-S3