Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function

Nonmuscle myosin light chain kinase (nmMLCK), a multi-functional cytoskeletal protein critical to vascular homeostasis, is highly regulated by tyrosine phosphorylation. We identified multiple novel c-Abl–mediated nmMLCK phosphorylation sites by mass spectroscopy analysis (including Y(231), Y(464), Y...

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Detalles Bibliográficos
Autores principales: Dudek, Steven M., Chiang, Eddie T., Camp, Sara M., Guo, Yurong, Zhao, Jing, Brown, Mary E., Singleton, Patrick A., Wang, Lichun, Desai, Anjali, Arce, Fernando T., Lal, Ratnesh, Van Eyk, Jennifer E., Imam, Syed Z., Garcia, Joe G. N.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982111/
https://www.ncbi.nlm.nih.gov/pubmed/20861316
http://dx.doi.org/10.1091/mbc.E09-10-0876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982111/
https://www.ncbi.nlm.nih.gov/pubmed/20861316
http://dx.doi.org/10.1091/mbc.E09-10-0876

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