Hypoxia Suppression of Bim and Bmf Blocks Anoikis and Luminal Clearing during Mammary Morphogenesis

Proper adhesion to extracellular matrix is critical for epithelial cell survival. Detachment from matrix signals results in apoptosis, referred to as anoikis. Selective apoptosis of cells that become detached from matrix is associated with the formation of a lumen in three-dimensional mammary epithe...

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Detalles Bibliográficos
Autores principales: Whelan, Kelly A., Caldwell, Sarah A., Shahriari, Kristina S., Jackson, S. RaElle, Franchetti, Lisa D., Johannes, Gregg J., Reginato, Mauricio J.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982135/
https://www.ncbi.nlm.nih.gov/pubmed/20861305
http://dx.doi.org/10.1091/mbc.E10-04-0353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982135/
https://www.ncbi.nlm.nih.gov/pubmed/20861305
http://dx.doi.org/10.1091/mbc.E10-04-0353

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