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Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly
Reduced levels of frataxin, an essential protein of as yet unknown function, are responsible for causing the neurodegenerative pathology Friedreich's ataxia. Independent reports have linked frataxin to iron–sulphur cluster assembly through interactions with the two central components of this ma...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982165/ https://www.ncbi.nlm.nih.gov/pubmed/20981023 http://dx.doi.org/10.1038/ncomms1097 |