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Pore-opening mechanism in trimeric P2X receptor channels

The opening of ion channels in response to ligand binding, voltage or membrane stretch underlies electrical and chemical signalling throughout biology. Two structural classes of pore-opening mechanisms have been established, including bending of pore-lining helices in the case of tetrameric cation c...

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Detalles Bibliográficos
Autores principales: Li, Mufeng, Kawate, Toshimitsu, Silberberg, Shai D., Swartz, Kenton J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982178/
https://www.ncbi.nlm.nih.gov/pubmed/20975702
http://dx.doi.org/10.1038/ncomms1048