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Parameter optimization by using differential elimination: a general approach for introducing constraints into objective functions

BACKGROUND: The investigation of network dynamics is a major issue in systems and synthetic biology. One of the essential steps in a dynamics investigation is the parameter estimation in the model that expresses biological phenomena. Indeed, various techniques for parameter optimization have been de...

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Detalles Bibliográficos
Autores principales: Nakatsui, Masahiko, Horimoto, Katsuhisa, Okamoto, Masahiro, Tokumoto, Yasuhito, Miyake, Jun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982696/
https://www.ncbi.nlm.nih.gov/pubmed/20840736
http://dx.doi.org/10.1186/1752-0509-4-S2-S9