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Evolution of the Antiretroviral Restriction Factor TRIMCyp in Old World Primates

The retroviral restriction factor TRIMCyp, which is a fusion protein derived from the TRIM5 gene, blocks replication at a post-entry step. Among Old World primates, TRIMCyp has been found in four species of Asian macaques, but not in African monkeys. To further define the evolutionary origin of Old...

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Detalles Bibliográficos
Autores principales: Dietrich, Elizabeth A., Jones-Engel, Lisa, Hu, Shiu-Lok
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982814/
https://www.ncbi.nlm.nih.gov/pubmed/21103414
http://dx.doi.org/10.1371/journal.pone.0014019