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Evolution of the Antiretroviral Restriction Factor TRIMCyp in Old World Primates
The retroviral restriction factor TRIMCyp, which is a fusion protein derived from the TRIM5 gene, blocks replication at a post-entry step. Among Old World primates, TRIMCyp has been found in four species of Asian macaques, but not in African monkeys. To further define the evolutionary origin of Old...
Autores principales: | Dietrich, Elizabeth A., Jones-Engel, Lisa, Hu, Shiu-Lok |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982814/ https://www.ncbi.nlm.nih.gov/pubmed/21103414 http://dx.doi.org/10.1371/journal.pone.0014019 |
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