Elastin Peptides Signaling Relies on Neuraminidase-1-Dependent Lactosylceramide Generation

The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex. In this work, we demonstrate that the receptor and lipid rafts colocalize at the plasma membrane. We also show that the disruption of...

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Detalles Bibliográficos
Autores principales: Rusciani, Anthony, Duca, Laurent, Sartelet, Hervé, Chatron-Colliet, Aurore, Bobichon, Hélène, Ploton, Dominique, Le Naour, Richard, Blaise, Sébastien, Martiny, Laurent, Debelle, Laurent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982818/
https://www.ncbi.nlm.nih.gov/pubmed/21103358
http://dx.doi.org/10.1371/journal.pone.0014010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982818/
https://www.ncbi.nlm.nih.gov/pubmed/21103358
http://dx.doi.org/10.1371/journal.pone.0014010

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