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Elastin Peptides Signaling Relies on Neuraminidase-1-Dependent Lactosylceramide Generation
The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex. In this work, we demonstrate that the receptor and lipid rafts colocalize at the plasma membrane. We also show that the disruption of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982818/ https://www.ncbi.nlm.nih.gov/pubmed/21103358 http://dx.doi.org/10.1371/journal.pone.0014010 |