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Multi-locus Test Conditional on Confirmed Effects Leads to Increased Power in Genome-wide Association Studies
Complex diseases or phenotypes may involve multiple genetic variants and interactions between genetic, environmental and other factors. Current genome-wide association studies (GWAS) mostly used single-locus analysis and had identified genetic effects with multiple confirmations. Such confirmed sing...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982824/ https://www.ncbi.nlm.nih.gov/pubmed/21103364 http://dx.doi.org/10.1371/journal.pone.0015006 |