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LXR Deficiency Confers Increased Protection against Visceral Leishmania Infection in Mice
BACKGROUND: The liver X receptors (LXRs) are a family of nuclear receptor transcription factors that are activated by oxysterols and have defined roles in both lipid metabolism and cholesterol regulation. LXRs also affect antimicrobial responses and have anti-inflammatory effects in macrophages. As...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982826/ https://www.ncbi.nlm.nih.gov/pubmed/21103366 http://dx.doi.org/10.1371/journal.pntd.0000886 |