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Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal illness whose pathogenesis remains poorly understood. Recent evidence suggests oxidative stress as a key player in the establishment/progression of lung fibrosis in animal models and possibly in human IPF. The aim of the pres...

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Detalles Bibliográficos
Autores principales: Bocchino, Marialuisa, Agnese, Savina, Fagone, Evelina, Svegliati, Silvia, Grieco, Domenico, Vancheri, Carlo, Gabrielli, Armando, Sanduzzi, Alessandro, Avvedimento, Enrico V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982828/
https://www.ncbi.nlm.nih.gov/pubmed/21103368
http://dx.doi.org/10.1371/journal.pone.0014003