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Fludarabine-based myeloablative regimen as pretransplant conditioning therapy in adult acute leukemia/myelodysplastic syndrome: comparison with oral or intravenous busulfan with cyclophosphamide

BACKGROUND: A combination of busulfan (Bu) and cyclophosphamide (Cy) has been used as a standard myeloablative regimen for allogeneic hematopoietic stem cell transplantation (HSCT). Recent studies postulate that fludarabine (Flu) is a less toxic substitute for Cy. METHODS: Forty-two patients who wer...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyun, Choi, Jimin, Kwon, Kyung A, Lee, Suee, Oh, Sung Yong, Kwon, Hyuk-Chan, Kim, Hyo-Jin, Han, Jin Yeong, Kim, Sung-Hyun
Formato: Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983027/
https://www.ncbi.nlm.nih.gov/pubmed/21120188
http://dx.doi.org/10.5045/kjh.2010.45.2.102