Induction of hypoxia-inducible factor-1α inhibits drug-induced apoptosis in the human leukemic cell line HL-60

BACKGROUND: Leukemic cells originate from hypoxic bone marrow, which protects them from anti-cancer drugs. Although many factors that cause drug resistance in leukemic cells have been studied, the effect of hypoxia on drug-induced apoptosis is still poorly understood. METHODS: In this study, we exam...

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Detalles Bibliográficos
Autores principales: Yook, Yeon-Joo, Seo, Young-Jin, Kang, Hyoung Jin, Ko, Sang-Hyeok, Shin, Hee Young, Lee, Jeong Jin, Jeong, Gajin, Ahn, Hyo Seop
Formato: Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983039/
https://www.ncbi.nlm.nih.gov/pubmed/21120203
http://dx.doi.org/10.5045/kjh.2010.45.3.158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983039/
https://www.ncbi.nlm.nih.gov/pubmed/21120203
http://dx.doi.org/10.5045/kjh.2010.45.3.158

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