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Mitotic spindle disassembly occurs via distinct subprocesses driven by the anaphase-promoting complex, Aurora B kinase, and kinesin-8

The mitotic spindle is a complex and dynamic structure. Although much has been learned about how spindles assemble and mediate chromosome segregation, how spindles rapidly and irreversibly disassemble during telophase is less clear. We used synthetic lethal screens in budding yeast to identify mutan...

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Detalles Bibliográficos
Autores principales: Woodruff, Jeffrey B., Drubin, David G., Barnes, Georjana
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983061/
https://www.ncbi.nlm.nih.gov/pubmed/21079246
http://dx.doi.org/10.1083/jcb.201006028