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G1 arrest and differentiation can occur independently of Rb family function

The ability of progenitor cells to exit the cell cycle is essential for proper embryonic development and homeostasis, but the mechanisms governing cell cycle exit are still not fully understood. Here, we tested the requirement for the retinoblastoma (Rb) protein and its family members p107 and p130...

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Detalles Bibliográficos
Autores principales: Wirt, Stacey E., Adler, Adam S., Gebala, Véronique, Weimann, James M., Schaffer, Bethany E., Saddic, Louis A., Viatour, Patrick, Vogel, Hannes, Chang, Howard Y., Meissner, Alex, Sage, Julien
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983066/
https://www.ncbi.nlm.nih.gov/pubmed/21059851
http://dx.doi.org/10.1083/jcb.201003048