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The cell biology of polycystic kidney disease

Polycystic kidney disease is a common genetic disorder in which fluid-filled cysts displace normal renal tubules. Here we focus on autosomal dominant polycystic kidney disease, which is attributable to mutations in the PKD1 and PKD2 genes and which is characterized by perturbations of renal epitheli...

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Detalles Bibliográficos
Autores principales: Chapin, Hannah C., Caplan, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983067/
https://www.ncbi.nlm.nih.gov/pubmed/21079243
http://dx.doi.org/10.1083/jcb.201006173