Cargando…

Cep152 interacts with Plk4 and is required for centriole duplication

Centrioles are microtubule-based structures that organize the centrosome and nucleate cilia. Centrioles duplicate once per cell cycle, and duplication requires Plk4, a member of the Polo-like kinase family; however, the mechanism linking Plk4 activity and centriole formation is unknown. In this stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Hatch, Emily M., Kulukian, Anita, Holland, Andrew J., Cleveland, Don W., Stearns, Tim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983069/
https://www.ncbi.nlm.nih.gov/pubmed/21059850
http://dx.doi.org/10.1083/jcb.201006049