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Cep152 interacts with Plk4 and is required for centriole duplication
Centrioles are microtubule-based structures that organize the centrosome and nucleate cilia. Centrioles duplicate once per cell cycle, and duplication requires Plk4, a member of the Polo-like kinase family; however, the mechanism linking Plk4 activity and centriole formation is unknown. In this stud...
Autores principales: | Hatch, Emily M., Kulukian, Anita, Holland, Andrew J., Cleveland, Don W., Stearns, Tim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983069/ https://www.ncbi.nlm.nih.gov/pubmed/21059850 http://dx.doi.org/10.1083/jcb.201006049 |
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