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Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
Both gain and loss of function studies have identified the Polo-like kinase Plk4/Sak as a crucial regulator of centriole biogenesis, but the mechanisms governing centrosome duplication are incompletely understood. In this study, we show that the pericentriolar material protein, Cep152, interacts wit...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983070/ https://www.ncbi.nlm.nih.gov/pubmed/21059844 http://dx.doi.org/10.1083/jcb.201007107 |