Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method

A simple and sensitive method was developed to separate the carcinogenic polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), and six of its oxidation metabolites generated by rat hepatic microsomes enriched with cytochrome P450 (CYP) 1A1, by high pressure liquid chromatography (HPLC). The H...

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Detalles Bibliográficos
Autores principales: Moserová, Michaela, Kotrbová, Věra, Aimová, Dagmar, Šulc, Miroslav, Frei, Eva, Stiborová, Marie
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984113/
https://www.ncbi.nlm.nih.gov/pubmed/21217860
http://dx.doi.org/10.2478/v10102-009-0024-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984113/
https://www.ncbi.nlm.nih.gov/pubmed/21217860
http://dx.doi.org/10.2478/v10102-009-0024-0

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