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Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method

A simple and sensitive method was developed to separate the carcinogenic polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), and six of its oxidation metabolites generated by rat hepatic microsomes enriched with cytochrome P450 (CYP) 1A1, by high pressure liquid chromatography (HPLC). The H...

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Detalles Bibliográficos
Autores principales:	Moserová, Michaela, Kotrbová, Věra, Aimová, Dagmar, Šulc, Miroslav, Frei, Eva, Stiborová, Marie
Formato:	Texto
Lenguaje:	English
Publicado:	Slovak Toxicology Society SETOX 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984113/ https://www.ncbi.nlm.nih.gov/pubmed/21217860 http://dx.doi.org/10.2478/v10102-009-0024-0

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