ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells

BACKGROUND: Unrepaired DNA double-stranded breaks (DSBs) cause chromosomal rearrangements, loss of genetic information, neoplastic transformation or cell death. The nonhomologous end joining (NHEJ) pathway, catalyzing sequence-independent direct rejoining of DSBs, is a crucial mechanism for repairin...

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Detalles Bibliográficos
Autores principales: Maas, Sarah A, Donghia, Nina M, Tompkins, Kathleen, Foreman, Oded, Mills, Kevin D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984387/
https://www.ncbi.nlm.nih.gov/pubmed/20979627
http://dx.doi.org/10.1186/1741-7007-8-132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984387/
https://www.ncbi.nlm.nih.gov/pubmed/20979627
http://dx.doi.org/10.1186/1741-7007-8-132

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