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ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells

BACKGROUND: Unrepaired DNA double-stranded breaks (DSBs) cause chromosomal rearrangements, loss of genetic information, neoplastic transformation or cell death. The nonhomologous end joining (NHEJ) pathway, catalyzing sequence-independent direct rejoining of DSBs, is a crucial mechanism for repairin...

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Detalles Bibliográficos
Autores principales:	Maas, Sarah A, Donghia, Nina M, Tompkins, Kathleen, Foreman, Oded, Mills, Kevin D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984387/ https://www.ncbi.nlm.nih.gov/pubmed/20979627 http://dx.doi.org/10.1186/1741-7007-8-132

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