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Edelfosine-induced metabolic changes in cancer cells that precede the overproduction of reactive oxygen species and apoptosis

BACKGROUND: Metabolic flux profiling based on the analysis of distribution of stable isotope tracer in metabolites is an important method widely used in cancer research to understand the regulation of cell metabolism and elaborate new therapeutic strategies. Recently, we developed software Isodyn, w...

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Detalles Bibliográficos
Autores principales: Selivanov, Vitaly A, Vizán, Pedro, Mollinedo, Faustino, Fan, Teresa WM, Lee, Paul WN, Cascante, Marta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984393/
https://www.ncbi.nlm.nih.gov/pubmed/20925932
http://dx.doi.org/10.1186/1752-0509-4-135