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Correlation between sequence conservation and structural thermodynamics of microRNA precursors from human, mouse, and chicken genomes
BACKGROUND: Previous studies have shown that microRNA precursors (pre-miRNAs) have considerably more stable secondary structures than other native RNAs (tRNA, rRNA, and mRNA) and artificial RNA sequences. However, pre-miRNAs with ultra stable secondary structures have not been investigated. It is no...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984420/ https://www.ncbi.nlm.nih.gov/pubmed/20977776 http://dx.doi.org/10.1186/1471-2148-10-329 |