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Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data

BACKGROUND: Developing the right drugs for the right patients has become a mantra of drug development. In practice, it is very difficult to identify subsets of patients who will respond to a drug under evaluation. Most of the time, no single diagnostic will be available, and more complex decision ru...

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Detalles Bibliográficos
Autores principales: Huang, Erich P, Fridlyand, Jane, Lewin-Koh, Nicholas, Yue, Peng, Shi, Xiaoyan, Dornan, David, Burington, Bart
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984428/
https://www.ncbi.nlm.nih.gov/pubmed/20979617
http://dx.doi.org/10.1186/1471-2407-10-586