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Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data
BACKGROUND: Developing the right drugs for the right patients has become a mantra of drug development. In practice, it is very difficult to identify subsets of patients who will respond to a drug under evaluation. Most of the time, no single diagnostic will be available, and more complex decision ru...
Autores principales: | Huang, Erich P, Fridlyand, Jane, Lewin-Koh, Nicholas, Yue, Peng, Shi, Xiaoyan, Dornan, David, Burington, Bart |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984428/ https://www.ncbi.nlm.nih.gov/pubmed/20979617 http://dx.doi.org/10.1186/1471-2407-10-586 |
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