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Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin

BACKGROUND: Only a few studies have addressed the molecular pathways specifically involved in carcinogenesis of the distal colon and rectum. We aimed to identify potential differences among genetic alterations in distal colon and rectal carcinomas as compared to cancers arising elsewhere in the larg...

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Detalles Bibliográficos
Autores principales: Pinheiro, Manuela, Ahlquist, Terje, Danielsen, Stine A, Lind, Guro E, Veiga, Isabel, Pinto, Carla, Costa, Vera, Afonso, Luís, Sousa, Olga, Fragoso, Maria, Santos, Lúcio, Henrique, Rui, Lopes, Paula, Lopes, Carlos, Lothe, Ragnhild A, Teixeira, Manuel R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984429/
https://www.ncbi.nlm.nih.gov/pubmed/20979647
http://dx.doi.org/10.1186/1471-2407-10-587