Cargando…

Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts

BACKGROUND: Prostate tumours are commonly poorly oxygenated which is associated with tumour progression and development of resistance to chemotherapeutic drugs and radiotherapy. Fibroblast growth factor 8b (FGF8b) is a mitogenic and angiogenic factor, which is expressed at an increased level in huma...

Descripción completa

Detalles Bibliográficos
Autores principales: Tuomela, Johanna, Grönroos, Tove J, Valta, Maija P, Sandholm, Jouko, Schrey, Aleksi, Seppänen, Jani, Marjamäki, Päivi, Forsback, Sarita, Kinnunen, Ilpo, Solin, Olof, Minn, Heikki, Härkönen, Pirkko L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984431/
https://www.ncbi.nlm.nih.gov/pubmed/21034500
http://dx.doi.org/10.1186/1471-2407-10-596