PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells

BACKGROUND: The function of BRCA1 in response to ionizing radiation, which directly generates DNA double strand breaks, has been extensively characterized. However previous investigations have produced conflicting data on mutagens that initially induce other classes of DNA adducts. Because of the fu...

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Detalles Bibliográficos
Autores principales: Hammond-Martel, Ian, Pak, Helen, Yu, Helen, Rouget, Raphael, Horwitz, Andrew A., Parvin, Jeffrey D., Drobetsky, Elliot A., Affar, El Bachir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984446/
https://www.ncbi.nlm.nih.gov/pubmed/21103343
http://dx.doi.org/10.1371/journal.pone.0014027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984446/
https://www.ncbi.nlm.nih.gov/pubmed/21103343
http://dx.doi.org/10.1371/journal.pone.0014027

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