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Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis

Toll-like receptors (TLRs) are a family of transmembrane pattern recognition receptors (PRR) that play a key role in innate and adaptive immunity by recognizing structural components unique to bacteria, fungi and viruses. TLR4 is the most studied of the TLRs, and its primary exogenous ligand is lipo...

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Detalles Bibliográficos
Autores principales: Guo, Jinsheng, Friedman, Scott L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984459/
https://www.ncbi.nlm.nih.gov/pubmed/20964825
http://dx.doi.org/10.1186/1755-1536-3-21