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Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis
Toll-like receptors (TLRs) are a family of transmembrane pattern recognition receptors (PRR) that play a key role in innate and adaptive immunity by recognizing structural components unique to bacteria, fungi and viruses. TLR4 is the most studied of the TLRs, and its primary exogenous ligand is lipo...
Autores principales: | Guo, Jinsheng, Friedman, Scott L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984459/ https://www.ncbi.nlm.nih.gov/pubmed/20964825 http://dx.doi.org/10.1186/1755-1536-3-21 |
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