The caenorhabditis elegans CDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells

BACKGROUND: Attenuation of the EGFR (Epidermal Growth Factor Receptor) signalling cascade is crucial to control cell fate during development. A candidate-based RNAi approach in C. elegans identified CDT-2 as an attenuator of LET-23 (EGFR) signalling. Human CDT2 is a component of the conserved CDT2/C...

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Detalles Bibliográficos
Autores principales: Poulin, Gino B, Ahringer, Julie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984460/
https://www.ncbi.nlm.nih.gov/pubmed/20977703
http://dx.doi.org/10.1186/1471-213X-10-109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984460/
https://www.ncbi.nlm.nih.gov/pubmed/20977703
http://dx.doi.org/10.1186/1471-213X-10-109

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