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Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice

OBJECTIVE: Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has been reported to have potential antioxidant properties. However, the role of HO-1 on hepatocyte apoptosis remains unclear. We aim to elucidate the effects of HO-1 on oxidative stress related hepatocellular apoptosis...

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Detalles Bibliográficos
Autores principales: Nan, YueMin, Wang, RongQi, Zhao, SuXian, Han, Fang, Wu, Wen Juan, Kong, LingBo, Fu, Na, Kong, Li, Yu, Jun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984485/
https://www.ncbi.nlm.nih.gov/pubmed/20979658
http://dx.doi.org/10.1186/1476-511X-9-124