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Deletion of 1.8-kb mRNA of Marek's disease virus decreases its replication ability but not oncogenicity

BACKGROUND: The 1.8-kb mRNA was reported as one of the oncogenesis-related genes of Marek's disease virus (MDV). In this study, the bacterial artificial chromosome (BAC) clone of a MDV field strain GX0101 was used as the platform to generate mutant MDV to examine the functional roles of 1.8-kb...

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Detalles Bibliográficos
Autores principales: Sun, Aijun, Li, Yanpeng, Wang, Jingyan, Su, Shuai, Chen, Hongjun, Zhu, Hongfei, Ding, Jiabo, Cui, Zhizhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984594/
https://www.ncbi.nlm.nih.gov/pubmed/21029474
http://dx.doi.org/10.1186/1743-422X-7-294