Cargando…

Deletion of 1.8-kb mRNA of Marek's disease virus decreases its replication ability but not oncogenicity

BACKGROUND: The 1.8-kb mRNA was reported as one of the oncogenesis-related genes of Marek's disease virus (MDV). In this study, the bacterial artificial chromosome (BAC) clone of a MDV field strain GX0101 was used as the platform to generate mutant MDV to examine the functional roles of 1.8-kb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Aijun, Li, Yanpeng, Wang, Jingyan, Su, Shuai, Chen, Hongjun, Zhu, Hongfei, Ding, Jiabo, Cui, Zhizhong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984594/ https://www.ncbi.nlm.nih.gov/pubmed/21029474 http://dx.doi.org/10.1186/1743-422X-7-294

Ejemplares similares

Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek's disease virus
por: Li, Yanpeng, et al.
Publicado: (2011)

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus
por: Sun, Peng, et al.
Publicado: (2020)

The construction and characterization of the bi-directional promoter between pp38 gene and 1.8-kb mRNA transcripts of Marek's disease viruses
por: Chen, Ruiai, et al.
Publicado: (2009)

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence
por: Sato, Jumpei, et al.
Publicado: (2022)

Marek’s Disease Virus Cluster 3 miRNAs Restrict Virus’ Early Cytolytic Replication and Pathogenesis
por: Liao, Yifei, et al.
Publicado: (2020)

Depression of Vaccinal Immunity to Marek’s Disease by Infection with Chicken Infectious Anemia Virus
por: Zhang, Yankun, et al.
Publicado: (2017)

Glutaminolysis and Glycolysis Are Essential for Optimal Replication of Marek’s Disease Virus
por: Boodhoo, Nitish, et al.
Publicado: (2020)

Increased Horizontal Transmission of Recombinant Marek’s Disease Virus Due to Reticuloendotheliosis Virus Long Terminal Repeat Is the Major Competitive Advantage of the Virus Being a Prevalent Strain
por: Su, Shuai, et al.
Publicado: (2019)

Positive Selection Drives Rapid Evolution of the meq Oncogene of Marek’s Disease Virus
por: Padhi, Abinash, et al.
Publicado: (2016)

Sequence analysis of Meq oncogene among Indian isolates of Marek's disease herpesvirus
por: Gupta, Mridula, et al.
Publicado: (2016)

A Novel Effective and Safe Vaccine for Prevention of Marek’s Disease Caused by Infection with a Very Virulent Plus (vv+) Marek’s Disease Virus
por: Liao, Yifei, et al.
Publicado: (2021)

Abrogation of Marek’s disease virus replication using CRISPR/Cas9
por: Hagag, Ibrahim T., et al.
Publicado: (2020)

Out of Sight, but Not Out of Mind: Aspects of the Avian Oncogenic Herpesvirus, Marek’s Disease Virus
por: Davidson, Irit
Publicado: (2020)

Transcriptome-wide N6-methyladenosine modification profiling of long non-coding RNAs during replication of Marek’s disease virus in vitro
por: Sun, Aijun, et al.
Publicado: (2021)

Revisiting cellular immune response to oncogenic Marek’s disease virus: the rising of avian T-cell immunity
por: Yang, Yi, et al.
Publicado: (2020)

Analysis of the mRNA Targetome of MicroRNAs Expressed by Marek’s Disease Virus
por: Parnas, Oren, et al.
Publicado: (2014)

Deletion of the Viral Thymidine Kinase in a Meq-Deleted Recombinant Marek’s Disease Virus Reduces Lymphoid Atrophy but Is Less Protective
por: Conrad, Steven J., et al.
Publicado: (2021)

Antiviral Effect of Lithium Chloride on Replication of Marek’s Disease Virus in Chicken Embryonic Fibroblasts
por: He, Huifeng, et al.
Publicado: (2021)

Visualization of Marek’s Disease Virus Genomes in Living Cells during Lytic Replication and Latency
por: Vychodil, Tereza, et al.
Publicado: (2022)

Inhibition of Marek’s Disease Virus Replication and Spread by 25-hydroxycholesterol and 27-hydroxycholesterol In Vitro
por: Kamble, Nitin, et al.
Publicado: (2023)

Newly detected mutations in the Meq oncogene and molecular pathotyping of very virulent Marek’s disease herpesvirus in Tunisia
por: Lachheb, Jihene, et al.
Publicado: (2020)

Transcriptional and Bioinformatic Analysis Provide a Relationship between Host Response Changes to Marek's Disease Viruses Infection and an Integrated Long Terminal Repeat
por: Cui, Ning, et al.
Publicado: (2016)

An mRNA expression-based signature for oncogene-induced replication-stress
por: Llobet, Sergi Guerrero, et al.
Publicado: (2022)

Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek’s Disease Virus Infection
por: Sun, Aijun, et al.
Publicado: (2022)

RIOK3-Mediated Akt phosphorylation facilitates synergistic replication of Marek’s disease and reticuloendotheliosis viruses
por: Du, Xusheng, et al.
Publicado: (2022)

Synergistic Viral Replication of Marek’s Disease Virus and Avian Leukosis Virus Subgroup J is Responsible for the Enhanced Pathogenicity in the Superinfection of Chickens
por: Zhou, Jing, et al.
Publicado: (2018)

UL28 and UL33 homologs of Marek’s disease virus terminase complex involved in the regulation of cleavage and packaging of viral DNA are indispensable for replication in cultured cells
por: Sun, Aijun, et al.
Publicado: (2021)

The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus
por: Warren, Wesley C., et al.
Publicado: (2023)

Mapping QTL Associated with Resistance to Avian Oncogenic Marek’s Disease Virus (MDV) Reveals Major Candidate Genes and Variants
por: Smith, Jacqueline, et al.
Publicado: (2020)

Self-excision of the BAC sequences from the recombinant Marek's disease virus genome increases replication and pathogenicity
por: Zhao, Yuguang, et al.
Publicado: (2008)

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E(2)
por: Boodhoo, Nitish, et al.
Publicado: (2019)

Marek's Disease Virus and Reticuloendotheliosis Virus Coinfection Enhances Viral Replication and Alters Cellular Protein Profiles
por: Du, Xusheng, et al.
Publicado: (2022)

Professor dr hab. Marek Ratajczak
por: Gadmer, Jean-Claude
Publicado: (2014)

The role of macrophages in classic Marek's disease.
por: Campbell, J. C.
Publicado: (1973)

Marek’s disease virus and skin interactions
por: Couteaudier, Mathilde, et al.
Publicado: (2014)

In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis
por: Guo, Hong, et al.
Publicado: (2016)

TRPV1 dysfunction in cystinosis patients harboring the homozygous 57 kb deletion
por: Buntinx, L., et al.
Publicado: (2016)

A 44-kb deleted-type copy number variation is associated with decreasing complement component activity and calf mortality in Japanese Black cattle
por: Sasaki, Shinji, et al.
Publicado: (2021)

Comparative analysis of oncogenic genes revealed unique evolutionary features of field Marek's disease virus prevalent in recent years in China
por: Tian, Mingxing, et al.
Publicado: (2011)

Co-Infection with Marek’s Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek’s Disease Vaccine Efficacy
por: Sun, Guo-Rong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lviuubkm5l02gtrfqmcncsh7ma