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Soluble perlecan domain i enhances vascular endothelial growth factor-165 activity and receptor phosphorylation in human bone marrow endothelial cells

BACKGROUND: Immobilized recombinant perlecan domain I (PlnDI) binds and modulates the activity of heparin-binding growth factors, in vitro. However, activities for PlnDI, in solution, have not been reported. In this study, we assessed the ability of soluble forms to modulate vascular endothelial gro...

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Detalles Bibliográficos
Autores principales: Muthusamy, Arivalagan, Cooper, Carlton R, Gomes, Ronald R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987766/
https://www.ncbi.nlm.nih.gov/pubmed/21047416
http://dx.doi.org/10.1186/1471-2091-11-43