Creation of a novel peptide with enhanced nuclear localization in prostate and pancreatic cancer cell lines

BACKGROUND: For improved uptake of oligonucleotide-based therapy, the oligonucleotides often are coupled to peptides that facilitate entry into cells. To this end, novel cell-penetrating peptides (CPPs) were designed for mediating intracellular uptake of oligonucleotide-based therapeutics. The novel...

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Detalles Bibliográficos
Autores principales: Lewis, H Dan, Husain, Ali, Donnelly, Robert J, Barlos, Dimitrios, Riaz, Sheraz, Ginjupalli, Kalyani, Shodeinde, Adetola, Barton, Beverly E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987774/
https://www.ncbi.nlm.nih.gov/pubmed/21029412
http://dx.doi.org/10.1186/1472-6750-10-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987774/
https://www.ncbi.nlm.nih.gov/pubmed/21029412
http://dx.doi.org/10.1186/1472-6750-10-79

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