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A danger of low copy numbers for inferring incorrect cooperativity degree
BACKGROUND: A dose-response curve depicts the fraction of bound proteins as a function of unbound ligands. Dose-response curves are used to measure the cooperativity degree of a ligand binding process. Frequently, the Hill function is used to fit the experimental data. The Hill function is parameter...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987788/ https://www.ncbi.nlm.nih.gov/pubmed/21040554 http://dx.doi.org/10.1186/1742-4682-7-40 |