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Bioluminescence Imaging Allows Monitoring Hepatitis C Virus Core Protein Inhibitors in Mice

BACKGROUND: The development of small molecule inhibitors of hepatitis C virus (HCV) core protein as antiviral agents has been intensively pursued as a viable strategy to eradicate HCV infection. However, lack of a robust and convenient small animal model has hampered the assessment of in vivo effica...

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Detalles Bibliográficos
Autores principales: Du, Juan, Zhao, Fang, Zhou, Yong, Yan, Hu, Duan, Xiang-guo, Liang, Sheng-qiang, Wang, Ying-li, Fu, Qiu-xia, Wang, Xiao-hui, Peng, Jian-chun, Zhan, Lin-sheng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987796/
https://www.ncbi.nlm.nih.gov/pubmed/21124971
http://dx.doi.org/10.1371/journal.pone.0014043