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Menin Links the Stress Response to Genome Stability in Drosophila melanogaster

BACKGROUND: The multiple endocrine neoplasia type I gene functions as a tumor suppressor gene in humans and mouse models. In Drosophila melanogaster, mutants of the menin gene (Mnn1) are hypersensitive to mutagens or gamma irradiation and have profound defects in the response to several stresses inc...

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Detalles Bibliográficos
Autores principales: Papaconstantinou, Maria, Pepper, Alicia N., Wu, Ying, Kasimer, Dahlia, Westwood, Tim, Campos, Ana Regina, Bédard, Pierre-André
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987805/
https://www.ncbi.nlm.nih.gov/pubmed/21124979
http://dx.doi.org/10.1371/journal.pone.0014049