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Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

Despite the ∼10(18) αβ T cell receptor (TCR) structures that can be randomly manufactured by the human thymus, some surface more frequently than others. The pinnacles of this distortion are public TCRs, which exhibit amino acid-identical structures across different individuals. Public TCRs are thoug...

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Detalles Bibliográficos
Autores principales: Miles, John J., Bulek, Anna M., Cole, David K., Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David A., Rizkallah, Pierre J., Sewell, Andrew K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987824/
https://www.ncbi.nlm.nih.gov/pubmed/21124993
http://dx.doi.org/10.1371/journal.ppat.1001198