Genome-Wide Association Meta-Analysis of Cortical Bone Mineral Density Unravels Allelic Heterogeneity at the RANKL Locus and Potential Pleiotropic Effects on Bone

Previous genome-wide association (GWA) studies have identified SNPs associated with areal bone mineral density (aBMD). However, this measure is influenced by several different skeletal parameters, such as periosteal expansion, cortical bone mineral density (BMD(C)) cortical thickness, trabecular num...

Descripción completa

Detalles Bibliográficos
Autores principales: Paternoster, Lavinia, Lorentzon, Mattias, Vandenput, Liesbeth, Karlsson, Magnus K., Ljunggren, Östen, Kindmark, Andreas, Mellstrom, Dan, Kemp, John P., Jarett, Caroline E., Holly, Jeff M. P., Sayers, Adrian, St. Pourcain, Beate, Timpson, Nicholas J., Deloukas, Panos, Davey Smith, George, Ring, Susan M., Evans, David M., Tobias, Jon H., Ohlsson, Claes
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987837/
https://www.ncbi.nlm.nih.gov/pubmed/21124946
http://dx.doi.org/10.1371/journal.pgen.1001217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987837/
https://www.ncbi.nlm.nih.gov/pubmed/21124946
http://dx.doi.org/10.1371/journal.pgen.1001217

Ejemplares similares